A Review of Progress on Targeting LDL Receptor-Dependent and -Independent Pathways for the Treatment of Hypercholesterolemia, a Major Risk Factor of ASCVD

Since the discovery of the LDL receptor in 1973 by Brown and Goldstein as LED Strips a causative protein in hypercholesterolemia, tremendous amounts of effort have gone into finding ways to manage high LDL cholesterol in familial hypercholesterolemic (HoFH and HeFH) individuals with loss-of-function mutations in the LDL receptor (LDLR) gene.Statins

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Cognitive Function, Mental Health, and Quality of Life in Siblings of Preterm Born Children: Protocol for a Systematic Review

BackgroundChildren and adults born preterm are at increased risk of cognitive impairments, mental health disorders, and poorer quality of life.Epidemiological studies have shown that the impact of preterm birth extends to the immediate family members; however, existing research have focused on parents, and little attention has been given to sibling

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FRACTAL DIMENSIONALITY ANALYSIS OF MAMMARY GLAND THERMOGRAMS

Thermography may enable early detection of a cancer tumour within a mammary gland at an early, treatable stage of the illness, but thermogram analysis methods must be developed Handbag to achieve this goal.This study analyses the feasibility of applying Jackets/Outerwear the Hurst exponent readings algorithm for evaluation of the high dimensionalit

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Discomfort glare from daylight in classrooms

Provision of daylight without the risk of discomfort glare is one of the aspects that determine the quality of the classroom environment.Although discomfort glare from daylight is under investigation for a long time, a knowledge gap concerning the applicability of the existing metrics to the spatial conditions of the classroom is identified in this

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